Carpal Tunnel Syndrome Research - Symptoms, Causes, Trauma, Diagnosis, Physiotherapy

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Medial thenar recording in normal subjects and carpal tunnel syndrome.

Wilder Smith EP, Chan YH, Kannan TA

Neurology, Yong Loo Lin School of Medicine, National University Singapore, Singapore. mdcwse@nus.edu.sg

OBJECTIVE: Since little is known about the involvement of median nerve fibres to the medial thenar eminence in CTS, we determine the consistency of a motor response derived from a medial thenar motor (MTM) site. We then compare sensitivity and specificity of this novel site with other nerve conduction parameters in supporting a diagnosis of CTS. METHODS: The motor responses over the MTM with ulnar and median stimulation were determined in healthy subjects and patients with CTS. Sensitivity and specificity of 4 motor techniques (Abductor Pollicis Brevis (APB) and median MTM latency, 2nd Lumbricales to Interossei latency difference (2-LINT), APB to Adductor Digiti Minimi (ADM) latency difference, median MTM to ulnar MTM latency difference) and the median sensory distal latency in confirming CTS were calculated using the ROC method. RESULTS: 132 hands (68 CTS, 64 controls) were examined. All but one median and ulnar nerve stimulation (both in patients with CTS) resulted in negative MTM compound muscle action potentials. Sensitivity and specificity in diagnosing CTS were 79/97% (APB) 90/98% (median MTM latency), 88/97% (2-LINT), 85/97% (APB to ADM latency difference) and 75/95% (median MTM to ulnar MTM latency difference). Median sensory latency showed 89% sensitivity and 97% specificity. CONCLUSIONS: Median and ulnar stimulation results in consistent motor responses at the medial thenar site. Median distal motor latency to MTM is frequently abnormal in CTS showing similar sensitivity and specificity to 2-LINT and median distal sensory latency. SIGNIFICANCE: The MTM site shows consistent responses to both median and ulnar stimulation. MTM distal latency can be considered a useful site for supporting a diagnosis of CTS.

Published 12 March 2007 in Clin Neurophysiol, 118(4): 757-61.
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Carpal Tunnel Syndrome Research Today Archive:

Volume 1 (2005)
  Issue 1 (October)
  Issue 2 (November)
  Issue 3 (December)

Volume 2 (2006)
  Issue 1 (January)
  Issue 2 (February)
  Issue 3 (March)
  Issue 4 (April)
  Issue 5 (May)
  Issue 6 (June)
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Volume 3 (2007)
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  Issue 5 (May)
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  Issue 10 (October)
  Issue 11 (November)
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Volume 4 (2008)
  Issue 1 (January)
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  Issue 4 (April)
  Issue 5 (May)
  Issue 6 (June)
  Issue 7 (July)
  Issue 8 (August)
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  Issue 10 (October)
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Carpal Tunnel Syndrome and Other Disorders of the Median Nerve

Carpal Tunnel Syndrome and Other Disorders of the Median Nerve